ACTN3 R577X polymorphism influences muscular power in Japanese athletes

2012 The American College of Sports Medicine

α-actinin-3(ACTN3) is one of most studied “performance genes” and have been reported with muscle composition, muscular strength and elite performance. To investigate whether ACTN3 R577X polymorphism would be associated with muscle power in Japanese collegiate athletes. METHODS: 105 male athletes and 243 controls (94 male and 149 female) were recruited in this study. Athletes performed 30s Wingate Anaerobic Test (WAnT) with a resistance equal to 7.5% of body weight. Genotyping was analyzed using TaqMan approach for the ACTN3 (rs1815739) polymorphism.　 The above data suggested that the ACTN3 RR and R allele would be influenced peak power of Wingate Anaerobic Test in Japanese collegiate athletes.
（本研究は、大学アスリートを対象にACTN3遺伝子多型と無酸素性作業能力との関連性を検討したものである。その結果、ウィンゲートテストのピークパワーにおいてRR型もしくはR alleleは有利に働くことが示された。また、30秒間の平均パワーにおいては関連性は認められなかったことについて報告したものである。）

Naoki Kikuchi, Dai Ueda, Koichi Nakazato, Min Seok-ki, Inkwan Hwang, Shouji Igawa